Abstract
In a previous article on steroid hormones as the sole treatment for patients with anogenital pruritus, 1 I concluded that these agents are effective when used to treat patients with cutaneous manifestations, namely lichenification, and symptoms severe enough to call for their use. No relief was obtained when pruritus was not accompanied by local skin changes. The response was also unsatisfactory in most instances of anal pruritus associated with proctologic lesions, such as fistulas, ulcers, and prolapsing hemorrhoids, the discharges of which irritate the anoperineal skin. Although these medicaments are not curative, they afford the patient gratifying symptomatic relief from pruritus and the clinician an opportunity to study the patient to determine causal mechanisms and to correct them fundamentally. Corticotropin (ACTH) administered parenterally, cortisone acetate administered orally, and hydrocortisone injected under the lichenified perianal skin were the medicaments studied. This report deals with the results obtained from topical application of
Published Version
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