Abstract

Polysomnography (PSG) is the gold-standard for sleep apnea and hypopnea syndrome (SAHS) diagnosis. Because the PSG system is not suitable for long-term continuous use owing to the high cost and discomfort caused by attached multi-channel sensors, alternative methods using a non-contact sensor have been investigated. However, the existing methods have limitations in that the radar-person distance is fixed, and the detected apnea hypopnea (AH) event cannot be provided in real-time. In this paper, therefore, we propose a novel approach for real-time AH event detection with impulse-radio ultra-wideband (IR-UWB) radar using a deep learning model. 36 PSG recordings and simultaneously measured IR-UWB radar data were used in the experiments. After the clutter was removed, IR-UWB radar images were segmented by sliding a 20-s window at 1-s shift, and categorized into two classes: AH and N. A hybrid model combining the convolutional neural networks and long short-term memory networks was trained with the data, which consisted of class-balanced segments. Time sequenced classified outputs were then fed to an event detector to identify valid AH events. Therefore, the proposed method showed a Cohen’s kappa coefficient of 0.728, sensitivity of 0.781, specificity of 0.956, and an accuracy of 0.930. According to the apnea-hypopnea index (AHI) estimation analysis, the Pearson’s correlation coefficient between the estimated AHI and reference AHI was 0.97. In addition, the average accuracy and kappa of SAHS diagnosis was 0.98 and 0.96, respectively, for AHI cutoffs of ≥ 5, 15, and 30 events/h. The proposed method achieved the state-of-the-art performance for classifying SAHS severity without any hand-engineered feature regardless of the user’s location. Our approach can be utilized for a cost-effective and reliable SAHS monitoring system in a home environment.

Highlights

  • Sleep apnea and hypopnea syndrome (SAHS) is the most common sleep-related breathing disorder in the general population and is caused by partial or complete obstruction of the upper airway [1]

  • After finding the optimal hyperparameters, we evaluated for apnea-hypopnea index (AHI) cutoff ≧ 5, 15, and 30 events/h was validated with the performance of the sleep apnea event detection for the ACC, SENS, SPEC, positive predictive value (PPV), and test dataset

  • apnea hypopnea (AH) events classified by the convolutional neural network (CNN)-long short-term memory (LSTM) model were compared with the scored AH events from the reference PSG

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Summary

Introduction

Sleep apnea and hypopnea syndrome (SAHS) is the most common sleep-related breathing disorder in the general population and is caused by partial or complete obstruction of the upper airway [1]. This disorder is characterized by repetitive events in which breathing is shallow or paused for more than 10s during sleep [2]. These events are typically accompanied by blood oxygen desaturation and arousals during sleep, leading to daytime sleepiness, decreased cognitive function and negative mood [3], [4].

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