Abstract
Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice.
Highlights
In aggregate, our repeated studies confirm the original conclusions of the manuscript, and independent research supports our originally reported conclusions
We provided immunological, histological, and physiological evidence that hyaluronan mediates the development of inflammation and airway hyperresponsiveness (AHR) after ozone inhalation [1]
After publication of our article, we became aware that the airway physiology measurements reported in Figs. 5, 6, and 9 of the original manuscript, which were provided by the animal pulmonary physiology laboratory at Duke University, may have been unreliable
Summary
Our repeated studies confirm the original conclusions of the manuscript, and independent research supports our originally reported conclusions. Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice. We provided immunological, histological, and physiological evidence that hyaluronan mediates the development of inflammation and airway hyperresponsiveness (AHR) after ozone inhalation [1].
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