Abstract
We report a case of human tick-borne encephalitis (TBE) in which the TBE virus was isolated from the biting tick. Viral growth and sequence were characterized and compared with those of a reference strain. Virus isolation from ticks from patients with TBE may offer a new approach for studies of epidemiology and pathogenicity.
Highlights
We report a case of human tick-borne encephalitis (TBE) in which the TBE virus was isolated from the biting tick
This study shows that tick bites can cause TBE, confirming earlier epidemiologic associations
TBE diagnosis was serologically confirmed, but TBE virus (TBEV) could not be isolated from the patient samples, which has been the case in previous studies (4,5)
Summary
We report a case of human tick-borne encephalitis (TBE) in which the TBE virus was isolated from the biting tick. In the serum samples from August 18, we could not detect any TBEV antibodies. TBEV quantitative PCR (qPCR) was performed as described (7) on all serum/plasma and CSF samples from the patient.
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