Abstract

For digital breast tomosynthesis (DBT) systems, we investigate the effects of the reconstruction filters for different data acquisition angles on signal detection. We simulated a breast phantom with a 30% volume glandular fraction (VGF) of breast anatomy using the power law spectrum and modeled the breast mass as a spherical object with a 1 mm diameter. Projection data were acquired using two different data acquisition angles and numbers of projection view pairs, and in-plane breast images were reconstructed using the Feldkamp-Davis-Kress (FDK) algorithm with three different reconstruction filter schemes. To measure the ability to detect a signal, we conducted the human observer study with a binary detection task and compared the signal detectability of human to that of channelized Hotelling observer (CHO) with Laguerre-Gauss (LG) channels and dense difference-of-Gaussian (D-DOG) channels. We also measured the contrast-to-noise ratio (CNR), signal power spectrum (SPS), and β values of the anatomical noise power spectrum (NPS) to show the association between human observer performance and these traditional metrics. Our results show that using a slice thickness (ST) filter degraded the signal detection performance of human observers at the same data acquisition angle. This could be predicted by D-DOG CHO with internal noise, but the correlation between the traditional metrics and signal detectability was not observed in this work.

Highlights

  • Breast cancer is the most commonly diagnosed cancer among women and the second-highest cause of cancer related mortality [1], but its high mortality rate has steadily decreased through advances in diagnostic imaging systems [2]

  • The main purpose of this work was to investigate the effects of reconstruction filters and data acquisition angles on human observer performance for in-plane digital breast tomosynthesis (DBT) images

  • Our results showed that the detection performance of human observers was dependent on the reconstruction filter schemes in the same data acquisition angle

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Summary

Introduction

Breast cancer is the most commonly diagnosed cancer among women and the second-highest cause of cancer related mortality [1], but its high mortality rate has steadily decreased through advances in diagnostic imaging systems [2]. Mammography systems are widely used for the early detection of breast cancer, but superimposed breast tissue is an impediment to degrade the lesion detection performance. Human observer performance on in-plane DBT images

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