Abstract

A three year study of the histological appearances of glutaraldehyde treated human fibrous dermal collagen allografts is reported. There was no immune or inflammatory response and no fibrous capsule was noted. The implants were colonised by host fibroblasts and blood vessels. No collagen resorption was observed. This type of preparation may offer an alternative to autogenous dermis grafts, with the advantages that it is both cell free and does not cause donor site scarring.

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