Huge craniopharyngioma: diffusion MRI and contrast-enhanced FLAIR imaging

Abstract

Craniopharyngiomas are most commonly located extraaxially in the suprasellar area. They are benign but aggressive neoplasms. An adult patient is reported to have a huge craniopharyngioma with gross extensions to the surroundings. In diffusion MRI, it had high signal for b=1000 mm 2/ s (true diffusion) images, and at the same time, high ADC values (=2.12 and 2.27×10 −3 mm 2/ s, compared to that of normal cerebellar parenchyma 0.85×10 −3 mm 2/s). In FLAIR images, obtained after administration of intravenous contrast medium, an intense, diffuse enhancement pattern was seen involving the viable tumor portions as well as the intratumoral fluid.