HUBUNGAN KOMORBIDITAS TERHADAP DERAJAT KEPARAHAN ADMISI DAN OUTCOME PASIEN COVID-19

Abstract

COVID-19 is a disease cause by SARS-CoV-2. One of the concerning clinical consideration is the presence of comorbid in patients. The purpose of this research is to identify the association between the comorbidities toward severity of admission and the outcome of COVID-19 patients at Bethesda Hospital Yogyakarta. The research was done observationally with a cross sectional design on 206 COVID-19 patients that was confirmed through RT-PCR at Bethesda Hospital Yogyakarta of June 2020 – June 2021 period. The comorbid data from COVID-19 patients will be analyzed in association to the severity of admission which is divided into mild, moderate, severe and critical degrees as well toward the outcome of COVID-19 patients. The data obtained were analyzed using the chi-square test with a significance level of 0.05. COVID-19 patients with comorbid were found 125 patients (60,68%). The most common comorbidities were cardiovascular disease (38,8%), followed by diabetes (31,6%), and kidney disease (12,1%). COVID-19 patients with two or more comorbidities as 59 (28.64%) and significantly have an association to the severity of admission and the outcome of the patient (p<0,001). The severity of severe (69%) and critical (89,4%) admissions was significantly higher in comorbid COVID-19 patients (p<0,001) and the mortality rate (88,6%) was significantly higher in case of comorbid COVID-19 patients (p<0,001), and COVID-19 patients who do not have comorbidities are 5,073 times more likely to be cured compared to patients who have comorbidities. There is an association between comorbidity toward severity of admission and outcome of COVID-19 patients.