Abstract
Circulating tumor DNA (ctDNA) testing has become a promising tool to guide first-line (1L) targeted treatment for advanced non-small cell lung cancer (aNSCLC). This study aims to estimate the clinical validity (CV) and clinical utility (CU) of ctDNA-based next-generation sequencing (NGS) for clinically relevant oncogenic driver mutations to inform 1L treatment decisions in aNSCLC with a systematic literature review and meta-analysis of currently available evidence.
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Schedule a callMore From: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
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