Abstract
Treatment of paroxysmal nocturnal hemoglobinuria (PNH) includes C5 complement inhibitors ravulizumab and eculizumab. Ravulizumab dosing varies by weight and includes a loading dose, followed by maintenance doses given every 8 weeks via intravenous infusion. This study investigated real-world dosing patterns of eculizumab-naive and eculizumab-experienced patients with PNH receiving ravulizumab.
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