Abstract
We present the case of lacrimal gland adenocarcinoma with apocrine metaplasia and a literature review for similar cases. A 65-year-old male with painless eyelid swelling was admitted to our hospital. A physical examination revealed tumor on the caudal side of the left orbital cavity, and a biopsy indicated apocrine adenocarcinoma. The patient underwent a total left orbital exenteration with eyelid resection and reconstruction using a deep inferior epigastric perforator skin flap. The pathological evaluation led to a definitive diagnosis of lacrimal gland adenocarcinoma with apocrine metaplasia. Lacrimal carcinomas are rare in the head and neck region, so there are few studies of lacrimal gland carcinoma with apocrine metaplasia. The rarity hinders extensive elucidation of the pathological characteristics and evidence-based treatment strategies.
Highlights
Hürthle cell carcinoma is a rare thyroid neoplasm with unpredictable development [1]
We describe a case of an 81-year-old male which after great diagnostic dilemma proved to be an aggressive Hürtle cell carcinoma
A 81-year-old man presented to the surgery clinic of our hospital with complaint of recurrent nodule in right lateral lymph node compartment (Level IIA)
Summary
Hürthle cell carcinoma is a rare thyroid neoplasm with unpredictable development. Ever since its first description in 1907 by Langhans there have been a debate about their origin, clinical course, treatment and prognosis. We describe a case of an 81-year-old male which after great diagnostic dilemma proved to be an aggressive Hürtle cell carcinoma. This case illustrates an aggressive Hürthle cell carcinoma with unpredictable slow progressive development and resistant to treatment options including surgery and radioactive iodine
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