Abstract
Plants synthesise many secondary metabolites which are of great medicinal value. Costus pictus also known as Insulin plant is considered as valuable medicinal plant in preparation of many commercial pharmaceutical products. The aim of the present study is to identify one such secondary metabolite flavonoid (Rutin) in the leaves of Costus pictus by HPLC method and also to evaluate the antioxidant potential of Ethyl acetate extract of Costus using DPPH and NO scavenging assay. The Extracted materi al was identified as Rutin by comparing with Standard Rutin. Both the samples showed similar retention time of 2.8 minutes. The extract showed maximum DPPH free radical scavenging activity with increase in concentration and IC50 of Nitric acid scavenging activity was found to be more for the Extract than the standard ascorbic acid and Rutin. From this study it is concluded that Costus pictus leaves extract can be used as natural food supplement.
 Asian J. Med. Biol. Res. June 2020, 6(2): 334-339
Highlights
Plants have been the major source of drug discovery for the treatment of various ailments including diabetes mellitus and its secondary complications in Indian and other ancient system of medicine in the world (Atanasov et al, 2015)
In the series of medicinal plants for the treatment of Diabetes mellitus, Costus pictus belonging to the family Costaceae with well-known pharmacological as well as beneficial properties is used in the recent years
The separation chromatogram of the standard, Extracted Rutin from the Costus is illustrated in the Figure 1
Summary
Plants have been the major source of drug discovery for the treatment of various ailments including diabetes mellitus and its secondary complications in Indian and other ancient system of medicine in the world (Atanasov et al, 2015). Intake of dietary phytochemicals is associated with health benefits. Non communicable diseases such as cancer and diabetes are considered as the major cause of morbidity and mortality worldwide (Howes and Simmonds, 2014). In the series of medicinal plants for the treatment of Diabetes mellitus, Costus pictus belonging to the family Costaceae with well-known pharmacological as well as beneficial properties is used in the recent years. Antidiabetic, antiinflammatory, hypolipidemic effect (Sethumathi et al, 2009; Mani et al, 2010).
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