Abstract
ObjectiveTo evaluate the diagnostic accuracy of Pipelle endometrial biopsies before surgical treatment of uterine bleeding disorders.DesignRetrospective analysis.SettingCounty Hospital unit specializing in operative hysteroscopy.InterventionsRoutine outpatient endometrium biopsies were taken from 628 patients because of uterine bleeding disorders. Of these patients, 249 underwent transcervical resection of the endometrium (TCRE) and 75 had a hysterectomy within 6 months.ResultsComparing the two subgroups ‘malignant’ and ‘benign’, the positive predictive value for endometrial malignancy was 100% (95% CI, 73.5–100). Insufficient tissue was obtained in five cases (1.5%); in three there were submucous fibroids, in one sampling took place after TCRE, and one patient had atrophic endometrium.ConclusionAdequate preoperative histological assessment of the endometrium is feasible with Pipelle biopsies, and they are highly accurate in detecting endometrial malignancy.
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