Abstract

BackgroundResearch participant recruitment is often fraught with obstacles. Poor response rates can reduce statistical power, threaten both internal and external validity, and increase study costs and duration. Military personnel are socialized to a specific set of laws, norms, traditions, and values; their willingness to participate in research may differ from civilians. The aims of this study were to better understand the views of United States (US) Veterans who served in Operation Enduring Freedom (OEF)/ Operation Iraqi Freedom (OIF) on research and motivators for participating in research to inform recruitment for a planned observational study of respiratory health in OEF/OIF Veterans.MethodsWe conducted 10 focus groups in a purposive sample of OEF/OIF Veterans (n = 89) in five US cities in 2015. Key topics included: reasons for participating or declining to participate in health-related research, logistics around study recruitment and conduct, compensation, written materials, and information sharing preferences for study results. Two authors independently coded the data using template analysis.ResultsParticipants identified three criteria that motivated a decision to participate in health-related research: 1) adequate compensation, 2) desire to help other Veterans, and 3) significance and relevance of the research topic. For many, both sufficient compensation and a sense that the study would help other Veterans were critical. The importance of transparency arose as a key theme; Veterans communicated that vague language about study aims or procedures engendered distrust. Lastly, participants expressed a desire for studies to communicate results of their specific health tests, as well as overall study findings, back to research participants.ConclusionsOEF/OIF Veterans described trust, transparent communication, and respect as essential characteristics of research in which they would be willing to participate. Additional studies are needed to determine whether our results generalize to other US Veterans; nevertheless, our results highlight precepts that have been reported as important for recruitment in other populations. Researchers may benefit from using community-engaged research methods to seek feedback on recruitment materials and strategies prior to initiating research. For costly studies targeting a large sample (i.e. in the thousands), it may be important to test a variety of recruitment strategies.

Highlights

  • Research participant recruitment is often fraught with obstacles

  • Recruitment of research participants is often fraught with obstacles [1] and is one of the largest costs associated with conducting trials and observational studies [2]

  • The current paper reports findings that generalize to other studies targeting United States (US) Operation Enduring Freedom/Operation Iraqi Freedom (OEF/Operation Iraqi Freedom (OIF)) Veterans and that may be relevant to research among Veterans of other eras and non-Veterans

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Summary

Introduction

Research participant recruitment is often fraught with obstacles. Poor response rates can reduce statistical power, threaten both internal and external validity, and increase study costs and duration. Recruitment of research participants is often fraught with obstacles [1] and is one of the largest costs associated with conducting trials and observational studies [2]. Failure to enroll the pre-specified sample size is likely to result in insufficient power. Even when sample size goals are met, participation must be independent of the exposure and outcome under study for the research to obtain unbiased results (i.e., high internal validity). High response rates are important in terms of generalizability (i.e., external validity). High response rates are necessary to keep studies on time and budget

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