Abstract
Kaempferia galanga L. is considered as a medicinal plant used in folkloric medicine and used in anti-inflammatory, analgesic, and anti-cancer,... Moreover, the essential oils from leaves is an incredients for medicines, perfumery, cosmetics, spices and mouthwash thanks to their antioxidant and antibacterial properties. The study is aimed to evaluate antioxidant activity in vitro and in vivo conditions of the ethanolic extract from rhizomes of Kaempferia galanga L.. The results showed that the ethanolic rhizomes extract displayed in vitro antioxidant activities using DPPH, ABTS+ and RP method, with the EC50 (effective concentration) values are 151.6±2.5 µg/mL, 2404.8±55 µg/mL and 116.5±4.8 µg/mL, respectively. In addition, D. melanogaster given extract-supplemented feed had resistance to stress conditions induced by H2O2 and paraquat better than those grown with standard food. Total polyphenol and flavonoid content were 54.42 mg GAE/g and 56.96 mg QE/g, respectively. These findings indicated that Kaempferia galanga L. is a very potential herb containing natural antioxidant compounds.
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