Abstract
Introduction. Despite the low rate of bacterial superinfections, COVID-19 pandemic has had a significant impact on the emergence of multiresistant bacteria, due to the abusive and excessive use of antibiotics. Our objective is to assess the hospital consumption of antibiotics during the COVID-19 pandemic. Materials and methods. This is a descriptive retrospective study, which assessed the impact of the COVID-19 pandemic on the hospital consumption of antibiotics at Batna University Hospital. We compared the consumption of antibiotics during the 3rd Covid-19 wave (July 2021August 2021) with that of the same period from 2019. Results. Comparing the two periods July - August 2021 to the same period in 2019, it was found that the total consumption of antibiotics increased considerably by 57.62% (21422.12 DDD in 2021 against 13590.88 DDD in 2019). Beta-lactam antibiotics are the most consumed family of antibiotics. Consumption of cefotaxime increased from 3579 DDD in 2019 to 9552.5 in 2021 DDD (an increase of 166.90%). In addition, the needs for imipenem and amoxicillin/clavulanic acid also increased by 53.20% and 23.73%, respectively in 2021. During the 3rd wave of Covid-19, the use of vancomycin, ciprofloxacin and levofloxacin increased by 81.19%, 91.90%, 480% respectively. Conclusion. Our results confirm the overconsumption of antibiotics during the Covid-19 pandemic. The emergence of resistant mutants remains the main consequence.
Published Version
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