Abstract

Aims: to revisited hospital route of infection transmission in patients under medical care with its related problems and re-focus on some important MDR nosocomial infection agents route of transmission to vulnerable patients. Discussion: Accidental infections acquired in hospitals or hospital acquired infection (HAI) is a global major health condition, and become a major obstacle in the present day era of hospitalization. Increased risk of morbidity with mortality, lengthened hospitalization, massive prescription of antibiotics, and socio-economically become a definite financial burden. Disinfection and sterilization in hospitals is of increasing concern. Besides that, the abuse of antibiotics has led to the prompt wide spread of multidrug-resistant drugs (MDR) microorganisms which is characterized by the ability to quickly adapt to an environment that previously does not support its growth commonly and able to initiate serious life-threatening HAI. The need to understand route of transmission and its associated obstacles will help combating MDR microorganisms. Conclusion: The Global emergence of MDR microorganisms with its difficult route of infections has created a major obstacle to combat the bacterial pathogens, and need serious attention from all stakeholders, throughout the world.

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