Hormonal study of the effect of sesame oil in female albino rats whose ovaries had been removed

Abstract

This study was conducted to investigate the physiological effect of sesame seed oil (Sesamum indicum) in the case of oral treatment on post-menopause and the occurrence of surgical menopause as a result of the removal of the ovaries, by studying the changes in some hormones in the blood serum of adult female albino rats (Albino Rats). as 15 adult rats about three months old, with weights ranging from 160-180 g were used. The animals were randomly divided into three groups with five animals for each group. The first group represented the negative control, which was normal without removal of the ovaries, and the second represented the positive control that was removed The ovaries were completely removed, and the third group completely removed the ovaries and treated them orally with sesame oil at a concentration of 4 ml/ kg of body weight per day for 30 days. The results of laboratory tests for serum samples of the completely removed ovaries group compared to the negative control group showed a significant decrease (P<0.05) in the levels of estrogen and progesterone, while an insignificant increase )P (0.05<in prolactin levels was observed, and significant (P<0.05) for follicle-stimulating hormone (FSH) and luteal stimulating hormone (LH).