Abstract
Abstract For protection of environmental insults and clear vision the outer most surface (the cornea) of the human eye has to be kept moist with the secretion of the lacrimal gland. During old age (in both the genders) and certain physiological conditions (in females) the pathophysiological conditions of lacrimal gland alter which results in Dry/Wet eye. Most of the menopausal women and young males and females face dry eye disorder due to environmental insults and therefore, we hypothesize that the acinar cells of lacrimal gland should have estrogen receptors. In support of this earlier we have localized estrogen receptors on eye lens epithelial cells that also regulated by sex steroid hormones.
Highlights
Hormonal Regulation of the Dry EyePD Gupta* Founder Director, Iladevi Cataract and IOL Research Centre, Ahmadabad, India
During menopausal transition years, many hormonal should have estrogen receptors
For the first time, we have shown involves tears - not making enough of them, having poor the estrogen receptors on the eye lens epithelium [3], but tear quality or rapid tear evaporation
Summary
PD Gupta* Founder Director, Iladevi Cataract and IOL Research Centre, Ahmadabad, India. The main sex hormone in women, can cause the cornea to become more elastic, changing the way light travels through the eye Both of these changes can lead to blurry vision and difficulty wearing contact lenses. The lacrimal gland secretes corneal disorders, irritation of lashes and hypersecretion a complex aqueous milieu rich in antibodies, cytotoxic of tears [13] This may be due to hormonal changes The agents and growth factors onto the ocular surface to cause of dry eyes is an imbalance in the composition of protect the cornea from desiccation, infection and the tears, decreased tear production or excessive tear vascularization while promoting wound healing and evaporation. Mucin, lipids, evaporate (get absorbed into the air) before the eyes get lysozyme, lactoferrin, lipocalin, lacritin, enough moisture--the most common cause of dry eyes This often happens when the glands that manufacture potassium.
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