Abstract
Over the years, modern medicines have evolved from use of a single drug to two or more drug combination to treat a particular disease as in the case of drug resistance. In addition, drugs given in combination with other substances/drugs often result in causing the synergistic effect to the various signaling proteins in the body. Many of these diseases like diabetes, cancer, and cardiovascular diseases are multifactorial in nature, and therefore, multidrug therapy is often recommended by physicians rather than mono-drug therapy in the current medical system. Traditional systems of medicines including TCM in China, the Ayurveda in India, the ATM in Africa, and others have been known generally as holistic medicines. They have not been accepted possibly due to the fact that they act in a different way with the western medicines. Fortunately, newer technologies such as the omics, systems biology, and bioinformatics are now providing justifications to the molecular basis of the mechanism of action of the phytopharmaceutical complexes in these drugs. When used together, these compounds either from mono- or multidrug extracts, the overall effect is expected to improve the efficacy of these drugs and also to minimize the adverse drug reactions (ARs).
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call