Abstract

HIV Drug Therapy in the Americas 16-18 April 2015, Mexico City, Mexico.

Highlights

  • Transgender people have specific health problems and challenges related to stigma, hormonal administration, sexual risk behaviour and application of body-modifying substances

  • Patients were divided in an Early highly active antiretroviral therapy (HAART) group and a Delayed HAART group those initiating more than four weeks after an opportunistic infection (OI)

  • hepatitis C virus (HCV) GT 1Á4 patients co-infected with human immunodeficiency virus (HIV) achieved high rates of sustained virologic response 12 weeks after treatment (SVR12) with an interferon-free, all-oral regimen of SOF ' RBV.This pooled analysis from two Phase 3 studies further demonstrates that SOF ' RBV treatment was well-tolerated and safely co-administered with multiple antiretroviral therapy (ART) regimens, and suggests that concurrent HIV-1 infection does not reduce SVR12 rates with sofosbuvir-based regimens

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Summary

Introduction

Transgender people have specific health problems and challenges related to stigma, hormonal administration, sexual risk behaviour and application of body-modifying substances. Conclusions: Efficiency of highly active antiretroviral therapy (HAART) among our prisons is higher compared to other cohorts [1]; the high frequency of comorbidities, smokers and drugs users, could increase the mortality and complicate HIV-infection by itself [2,3]; the high prevalence of HCV and HBV could be indicative of potentially risky blood-borne exposures or unprotected sexual contacts. Conclusions: Known factors associated with HIV infection such as low CD4 count and a high viral load are predictors of cytological alterations in this group of patients. Conclusions: UAg increased the diagnosis rate of histoplasmosis and has higher sensitivity than other serological tests based on antibodies These preliminary findings suggest that screening for histoplasmosis infection among PLWH and advanced disease in our setting might be an effective strategy to improve clinical care of PLWH. Under optimal patient’s compliance, a DRV/r-containing regimen with at least 2.5 fully active drugs is highly effective in routine clinical practice

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