Abstract
Background:Ovaries are the third leading site of cancer among women trailing behind cervical and breast cancer according to the Indian cancer registries. The spectrum of ovarian lesions is wide with harmless simple cystic lesions at one end and the fatal aggressive malignant lesions at the other end. Thus, ovarian neoplasm offers a good field for research. The present study is aimed to observe the frequency of neoplastic and non-neoplastic lesions in a tertiary care centre of rural India. Methods: This was a prospective two years observational study and was conducted at the Department of Pathology SRTR GMC, Ambajogai, including 185 ovarian lesions. Result: Total 185 ovarian lesions were studied, 101 cases were non-neoplastic while 84 cases were neoplastic. The most common non-neoplastic lesion was corpus luteal cyst (27.7%) followed by simple ovarian cyst (24.7%) and follicular cyst (21.8%). Among 84 neoplastic cases, 74 cases (88.1%) were benign,02 cases (2.4%) were borderline tumours and 08 cases (9.5%) were diagnosed malignant. Surface epithelial tumours contributed 75% cases, while germ cell tumours and sex-cord stromal tumourcontributed 20.8% and 4.8% respectively. Conclusions: Both non-neoplastic as well as neoplastic lesions of ovary often present with similar clinical and radiological features. So histopathological study is essential to diagnose ovarian tumours and predict their prognosis.
Highlights
The ovary has three main histologic compartments i.e. the surface Mullerian epithelium, the germ cells and the sex-cord stromal cells
The most common non-neoplastic lesion was corpus luteal cyst (27.7%) followed by simple ovarian cyst (24.7%) and follicular cyst (21.8%)
Only 185 cases were included in the present study, with 101 nonneoplastic ovarian lesions and 84 neoplastic ovarian lesions(Table 1)
Summary
The ovary has three main histologic compartments i.e. the surface Mullerian epithelium, the germ cells and the sex-cord stromal cells. Each compartment gives rise to distinct non-neoplastic and neoplastic lesions [1,2]. Such lesions can be found from neonatal to postmenopausal ages and it accounts for around 30% of all female genital. Indian trend analysis reveals a steady increase in the agestandardized incidence rate of ovarian cancer ranging from 0.26% to 2.44% per year in different area registries [4]. A few of the benign lesions can be confused with neoplasm clinically, intra-operatively or on histopathological examination. Result: Total 185 ovarian lesions were studied, 101 cases were non-neoplastic while 84 cases were neoplastic. Conclusions: Both non-neoplastic as well as neoplastic lesions of ovary often present with similar clinical and radiological features. Histopathological study is essential to diagnose ovarian tumours and predict their prognosis
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