Abstract
This work was conducted to evaluate the histopathological effects of probiotic (Biomin) and the toxic action of lead acetate on the intestine of one day old forty Ross broiler chicks. The probiotic was used in recommended dose (1.5g/Kg diet), lead acetate was used in toxic dose of (320mg/kg diet). Results show that the histopathological changes of animal group that was treated with lead acetate in toxic dose for 28 days represent the presence of necrosis at the apex of villi with desquamation and hyperplasia in the epithelium of villi and intestinal gland, while sections of chick intestine that were treated with lead acetate at toxic dose and probiotic at recommended dose for 28 days show the infiltration of lymphocyte in submucosal layer and focal area of coagulative necrosis in muscular layer. The group taken probiotic alone shows mild vascular degeneration when compared with the control group.
Highlights
Lead (Pb) is considered to be one of the major environmental pollutants and has been incriminated as a cause of accidental poisoning in domestic animals and birds more than any other substances (NRC, 1984), and environmental pollution with lead is a common occurrence in cities and their edges, significant pollution is more likely to occur near smelters or other industrial enterprises, or near major highways where posture is contaminated by exhaust fumes of automobiles (Blood and Rodostits, 1989)
Results show that the histopathological changes of animal group that was treated with lead acetate in toxic dose for 28 days represent the presence of necrosis at the apex of villi with desquamation and hyperplasia in the epithelium of villi and intestinal gland, while sections of chick intestine that were treated with lead acetate at toxic dose and probiotic at recommended dose for 28 days show the infiltration of lymphocyte in submucosal layer and focal area of coagulative necrosis in muscular layer
Effect on feed conversion ratio: some studies show that probiotics supplementation in feed of chickens improve the feed convertion ratio (Jagdish and Sen, 1993; Ergun et al, 2000), and it is reported in recent years that probiotics have detoxification action on heavy metals (Ibrahim et al, 2006), our goal from the present work is to evaluate the effects of probiotics on lead acetate absorption and toxicity in the intestine of broiler chickens
Summary
Lead (Pb) is considered to be one of the major environmental pollutants and has been incriminated as a cause of accidental poisoning in domestic animals and birds more than any other substances (NRC, 1984), and environmental pollution with lead is a common occurrence in cities and their edges, significant pollution is more likely to occur near smelters or other industrial enterprises, or near major highways where posture is contaminated by exhaust fumes of automobiles (Blood and Rodostits, 1989). ABSTRACT This work was conducted to evaluate the histopathological effects of probiotic (Biomin) and the toxic action of lead acetate on the intestine of one day old forty Ross broiler chicks.
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