Abstract

Background: Soft tissue tumors are a diverse group of lesions arising from the supporting soft tissue of the body. Though pathologically diverse, they frequently exhibit similar clinical presentations and radiological features. Correct histopathological diagnosis is therefore crucial for further management. 
 Aim/Objectives: To evaluate the spectrum of benign as well as malignant soft tissue tumors in a tertiary care centre in North India.
 Material and Methods: This retrospective study was carried out in the Department of Pathology from April 2017 to March 2018. All cases of soft tissue tumors in this period were included in the study. Gross findings were recorded from Histopathology request forms. Histology slides stained with haematoxylin and eosin stain were reviewed and findings recorded. 
 Results: Majority of patients were males with maximum cases in the 4th decade. Of all soft tissue tumors, 90.4% were benign, 4.0 % intermediate and 5.6% were malignant. Benign Adipocytic tumors (48.0%) were the commonest soft tissue tumors, followed by benign vascular tumors (24.0%). Malignant Fibrous Histiocytoma was the commonest malignant neoplasm in our study (42.8 %).
 Conclusions: Soft tumors pose diagnostic challenges because of confounding morphological characteristics. The incidence of benign tumors (90.4%) was much higher than malignant tumors in our study with benign lipomatous tumors (48.0%) being most common tumors.
 Keywords: Histopathology; Tumors; Lipomatous; Malignant

Highlights

  • Soft tissue tumors are defined as mesenchymal proliferation occurring in extra-skeletal non-epithelial tissue of the body, excluding the viscera, covering of brain and lymphoreticular system [1]

  • The peak age incidence for malignant tumors was in 6th decade while for benign tumors it was 3rd decade

  • Majority of the benign tumors were located in head and neck region (61.9%) while majority of malignant tumors had predilection of extremities (85.7%)

Read more

Summary

Introduction

Soft tissue tumors are defined as mesenchymal proliferation occurring in extra-skeletal non-epithelial tissue of the body, excluding the viscera, covering of brain and lymphoreticular system [1]. These are a heterogeneous group of tumors that are classified on histogenetic basis according to the adult tissue they resemble. Majority of soft tissue tumors are benign while malignant mesenchymal neoplasms amount to less than 1% of the overall malignant tumors in the body. The study was performed to evaluate the spectrum of soft tissue tumors in a tertiary care centre in North India. Aim/Objectives: To evaluate the spectrum of benign as well as malignant soft tissue tumors in a tertiary care centre in North India.

Methods
Results
Conclusion
Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call