Histopathological evaluation of uterine lesions in women with AUB in Vindhya region of Madhya Pradesh

Abstract

: Females over 20 years of age come frequently to gynecological clinics, with the complaint of Abnormal Uterine Bleeding (AUB). It has a direct impact on the physical and mental health of females. This research aims to detect the frequency of different uterine causes of AUB and determine the relationship between histopathological lesions associated with AUB and their age groups of presentation.: Endometrial biopsies / hysterectomy specimens were collected from 235 patients who presented with AUB to Department of Obstetrics & Gynecology SSMC, Rewa, M. P. (India), and HPE was carried out on all biopsies/specimens. Frequency of all findings was recorded and divided into organic and functional causes. Statistical analysis was done between histopathological lesions associated with AUB and their age groups of presentation.: Majority of cases (40%) belonged to 41-50 years of age. HPE revealed prolife rative pattern of endometrium, which was the most common presentation (24.68%) amongst functional causes, while the most common organic cause was uterine leiomyoma (12.76%). Cases of endometrial polyp and endometrial hyperplasia without atypia were found frequently in women of 41-50 years of age. The frequency of endometrial carcinoma was 1.27%, which commonly affected elderly females. : We conclude that AUB most commonly affects women in the perimenopausal age group. Histopathological study of uterine lesions aids the early diagnosis of premalignant and malignant lesions and thus saves the patient from having an unnecessary hysterectomy in premalignant lesions.