HISTOMORPHOLOGICAL STUDY OF ENDOMETRIAL BIOPSIES OF PERIMENOPAUSAL WOMEN IN ABNORMAL UTERINE BLEEDING -A STUDY AT TERTIARY CARE CENTRE

Abstract

Background: Abnormal uterine bleeding (AUB) is one of the common complaints in women in perimenopausal age group. Endometrial sampling is needed to investigate the cause of AUB. Aim: This study was conducted to evaluate the causes of AUB in perimenopausal age group and endometrial sampling by dilatation and curettage to identify various endometrial pathological patterns. Study Design: A type of prospective observational study conducted in department of pathology JMC Jhalawar. Materials And Methods: This study was done at the Department of Pathology, Jhalawar Medical College, Jhalawar during the period of one year from October 2020 to October 2021. Perimenopausal women (41-50 yrs.) with AUB who underwent dilatation and curettage were included in the study. Result: The commonest histopathological nding was secretory endometrium (38.33%) followed by proliferative endometrium (27.5%), hormonal imbalance (9.16%), simple hyperplasia without atypia (6.66%), disordered proliferative endometrium (5.83%) product of gestation (3.33%), menstrual endometrium (2.5%), chronic endometritis (1.66%) and endometrial polyp (0.83%). Endometrial carcinoma was diagnosed in 4 patients (3.33%). Conclusion: Endometrial causes of AUB evaluated by histopathological examination of curettings revealed that proliferative and secretory endometrium was the commonest diagnosis followed by hormonal imbalance.