Histomorphological Spectrum of Juvenile Salivary Gland Swelling: A Retrospective Case Series Study

Abstract

Abstract Background: Salivary gland neoplasms are a rare group of disorders with diverse morphologies and are even rarer in pediatric population. Aims and Objectives: This aimed to explore our experience with the histomorphological spectrum of salivary gland tumors in a tertiary care pediatric referral center so that it can add to the cumulative knowledge to these tumors. Materials and Methods: The histopathology records from the department of pathology from January 2012 to December 2020 were reviewed in retrospect. Perisalivary gland region lesions were excluded from the study. Results: A total of 50 cases were included in the study. The most common location for salivary gland masses was parotid region (70%). Nonneoplastic lesions were seen in 3 (6%) patients and neoplastic lesions were seen in 47 (94%) patients. The most found benign lesion of salivary gland tissue origin was pleomorphic adenoma and 10 out of 15 cases (66.7%) of malignant tumors were found to be mucoepidermoid carcinoma on histology. Conclusion: Salivary gland tumors, rare in childhood and adolescence, differ in their incidence and prognosis from those in adult patients. The percentage of malignant salivary gland tumors compared with benign is much more frequent than in adults. The parotid is the most common site, and mucoepidermoid carcinoma is the most common malignant tumor.