Abstract
Histological and Immunohistochemical Study on the Toxic Effects of Anthracene on the lung and liver of Adult Male Albino Rats and the Possible Protective Role of Ocimum gratissimum Extract
Highlights
Anthracene is one of a group of chemicals called polycyclic aromatic hydrocarbons (PAHs)
Our results showed that anthracene induced disrupted lung architecture with collapsed alveoli, inflammatory cellular infiltration, congested thickened pulmonary vessels and extravasated red blood cells
The aim of this study was to demonstrate the effect of anthracene on the lung and liver of adult male albino rats and evaluate the possible protective role of basil
Summary
Anthracene is one of a group of chemicals called polycyclic aromatic hydrocarbons (PAHs). Industries where exposure to PAHs is likely to occur include coke ovens and coal tar use, iron and steel works, aluminum works, foundries, carbon electrode and carbon black manufacture, asphalt manufacture and use, and many others. In these industries inhalation of volatile compounds or of particles with adsorbed PAHs and dermal absorption of mixtures containing PAHs may be important routes of exposure [4]. O. gratissimum is an antioxidant with volatile oils that contain phenolic eugenols, saponins, flavonoids, phenylpropanoids, linalool, and alkaloids as pharmacologically active agents. The aim of this study was to demonstrate the effect of anthracene on the lung and liver of adult male albino rats and evaluate the possible protective role of basil
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