Abstract
Abstract Objective To evaluate the bone repair associated with the use of biphasic ceramics based on hydroxyapatite and β-tricalcium phosphate (HA/TCP) in the procedures of maxillary sinus membrane elevation in human beings. Material and method Ten patients with a residual bone ridge in the posterior maxillary region between 3 mm and 5 mm in height were selected and indicated for procedures of bone grafting associated with maxillary sinus lift procedure. The maxillary sinuses were filled with HA/TCP, and after 8 months, the implants were implanted and a bone biopsy was collected with the aid of a trephine drill, which was then submitted to histological analysis for the evaluation of the composition of the grafted area. Result The histological description analysis of the biopsies revealed the presence of vital and immature bone tissue, juxtaposed to the biomaterial. Histomorphometric analysis showed that the biopsy composition was in average 28.8%, 27.4%, and 43.6% of bone tissue, biomaterial, and soft tissue, respectively. Conclusion The areas grafted with HA/TCP presented the adequate amount of bone formation that allowed the implantation of the implants. The success of the grafting procedure with this biomaterial was associated with its osteoconduction potential that allowed the formation of bone tissue in close contact with HA/TCP.
Highlights
The installation of osteointegratable implants is a viable and predictable alternative for the rehabilitation of edentulous ridges
This study demonstrated that the use of biphasic ceramics based on hydroxyapatite and β-tricalcium phosphate used as a graft material in maxillary sinus surgeries promoted the formation of bone tissue in intimate contact with the remaining biomaterial particles which allowed the installation of the osseointegrated implant after 8 months of the surgical procedure of grafting
A clinical study comparing histologically and histomorphometrically the biphasic ceramic grafts with autogenous bone grafts in maxillary sinus lift surgeries found that the biopsies taken from the areas grafted with biphasic ceramic presented 28.2% of bone tissue and 32.9% of biomaterial after a waiting period between 6-8 months of the grafting procedure and implant installation, and that the autogenous bone graft presented a greater amount of neoformed bone tissue (36.8%), this difference did not influence the clinical results of the implants installed in this study[8]
Summary
The installation of osteointegratable implants is a viable and predictable alternative for the rehabilitation of edentulous ridges. The posterior maxillary region is considered a critical area for the implant installation since frequently dental extraction associated with maxillary sinus pneumatization promotes bone. The group of alloplastic biomaterials has been very indicated among the biomaterials as an alternative to the use of autogenous bone due to its good osteoconduction property that allows the implants and maintenance of clinical results with high survival rates[9]. It has been reported that the action of this biomaterial to promote bone formation is associated with reabsorption of the β-tricalcium phosphate portion, which may induce osteoblastic differentiation, and the maintenance of hydroxyapatite, which allows the process of osteoconduction and reduction of resorption of the body of the biomaterial in comparison to alloplastic grafts constituted of pure β-tricalcium phosphate[10,13,14]. The aim of this study was to evaluate histologically the use of biphasic ceramics based on 60% hydroxyapatite and 40% β-tricalcium phosphate on procedures to elevate the maxillary sinus membrane in human beings
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
