Abstract

Histochemical examinations including demonstration of acid phosphatase, alkaline phosphatase, ATPase, non‐specific esterase and various oxydative enzymes were performed on biopsy specimens from patients with fatty liver caused by moderate alcohol consumption. In the fatty livers degeneration changes was found by demonstrating lysosomal changes by acid phosphatase reaction. By means of non‐specific esterase and oxydative enzyme reactions both degenerating and regenerating cells were found. Lack of enzyme activity in cells and morphological changes in the reaction product of NADH‐diaphorase indicated mitochondrial damage. ATPase and alkaline phosphatase demonstrated the sinusoids and biliary capillaries. Displacement of the biliary capillaries was found in some of the livers presenting fatty degeneration.

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