HISTOCHEMICAL EVALUATION OF THE PROCESSES OF PROTEIN OXIDATIVE MODIFICATION IN THE FIBRINOID OF THE PLACENTAL BASAL LAMINA COMBINED WITH PLACENTAL INFLAMMATION AND IRONDEFICIENCY ANEMIA OF GRAVIDAS

Abstract

The results of the research based on histochemical reactions with Bromophenol Blue on “acidic” and “basic” proteins according to Mikel Calvo method have found the following. A moderate intensification of the processes of protein oxidative modification is observed in iron-deficiency anemia in the fibrinoid of basal lamina in comparison with physiological pregnancy. There is a significant increase in the intensity of protein oxidative modification in the fibrinoid of basal lamina except acute form of chorioamnionitis. Underlying iron-deficiency anemia in various forms of inflammation in the placenta significantly affects the processes of protein oxidative modification in the fibrinoid of basal lamina in case of chronic inflammation of the placenta only.