Abstract

Introduction: We undertook this study to know the sensitivity, specificity and post-test probabilities of hip aspiration when diagnosing periprosthetic hip infections. We also examined “dry tap” (injection with saline and aspiration) results and aspiration volumes. Methods: This is a retrospective cohort study of patients aspirated for suspected periprosthetic joint infection between July 2012 and October 2016. All aspirations were carried out by one trained surgical care practitioner (SCP). All aspirations followed an aseptic technique and fluoroscopic guidance. Aspiration was compared to tissue biopsy taken at revision. Aspiration volumes were analysed for comparison. Results: Between January 2012 and September 2016, 461 hip aspirations were performed by our SCP. Of these 125 progressed to revision. We calculated sensitivity 59 % (confidence interval (CI) 35 %–82 %) and specificity 94 % (CI 89 %–98 %). Pre-test probability for our cohort was 0.14. Positive post-test probability was 0.59 and negative post-test probability 0.06. Aspiration volume for infected () and non-infected () joints was compared and showed no significant difference. Dry taps were experienced five times; in each instance the dry tap agreed with the biopsy result. Conclusions: Our data show that hip aspiration culture is a highly specific investigation for diagnosing infection but that it is not sensitive. Aspiration volume showed no significant difference between infected and non-infected groups. Each time a joint was infiltrated with saline to achieve a result, the result matched tissue sampling.

Highlights

  • We undertook this study to know the sensitivity, specificity and post-test probabilities of hip aspiration when diagnosing periprosthetic hip infections

  • Patients were included in the study if they had a hip aspiration for suspected Periprosthetic joint infection (PJI) and had progressed to revision, and patients were excluded if they had not progressed to revision

  • For our population of patients aspirated for suspected PJI, we calculated a pre-test probability of infection to be 0.14

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Summary

Introduction

We undertook this study to know the sensitivity, specificity and post-test probabilities of hip aspiration when diagnosing periprosthetic hip infections. CRP and ESR are sensitive but not specific (Piper et al, 2010), whereas synovial fluid aspiration is an invasive test with operator-dependent success rates (Tingle et al, 2016). In our institution the majority of hip aspirations for suspected PJI are carried out by a single trained orthopaedic surgical care practitioner (SCP). This approach has been proven to lower the rate of dry tap aspirations (Tingle et al, 2016).

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