Highly sensitive detection of photo-thermal transient stress by a sub-nanosecond pump probe with surface plasmon resonance

Hayato Ichihashi,Hiromichi Hayashi,Mami Matsukawa,Shinji Takayanagi,Yoshiaki Watanabe

doi:10.1063/1.5045750

Hayato Ichihashi, Hiromichi Hayashi + Show 3 more

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https://doi.org/10.1063/1.5045750

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Abstract

Photoacoustic microscopy (PAM) has attracted increasing attention for non-invasive functional imaging in biomedicine and biomedical studies. The surface plasmon resonance (SPR) sensor is a potential acoustical detector with high sensitivity and wide bandwidth for use in high-resolution 3D PAM. In this study, we investigated a simple Kretschmann SPR sensor, demonstrating highly sensitive stress detection in the sub-nanosecond timescale by directly inducing photo-thermal transient stress. To do this, we designed and used a sub-nanosecond pump probe system. The SPR sensor clearly detected the transient response from the thermal elastic effect, while a simple pump-probe sensor without SPR did not detect it. Our experimental results demonstrate a simple SPR sensor that can detect stress with high sensitivity and sub-nanosecond time resolution. This technique could be used in high-resolution 3D PAM by mounting a small biomedical sample on the sensor.

Highlights

Sensitive detection of photo-thermal transient stress by a sub-nanosecond pump probe with surface plasmon resonance
The almost photoacoustic microscopy (PAM) system is based on the time-domain PA system which makes use of the pulse laser and the piezoelectric acoustic transducer frequency-domain and phase-domain PA systems are studied.[12,13]
Obtaining high-resolution 3D images requires wide band detection of high-frequency ultrasound because the axial resolution of this technique depends on the pulse width of generated photoacoustic wave

Summary

Introduction

Sensitive detection of photo-thermal transient stress by a sub-nanosecond pump probe with surface plasmon resonance. The ultrafast response of an SPR stress sensor comes from the very short interaction time, on the order of picoseconds, between the acoustic stress and the light-plasmon coupling.[17] Studies of pump-probe measurements with a picosecond or femtosecond pulsed laser system have demonstrated highly sensitive sensing of stress due to a transient thermal elastic effect or a coherent phonon based on SPR, implying that SPR sensors show excellent detection at high frequencies.[18,19,20,21]

Results

Conclusion