Highly enantioselective immobilized prolinamide-catalyzed aldol reactions in continuous-flow systems: effect of water on the catalyst lifetime and application in the synthesis of a chiral fenpentadiol analogue

Caizhen Yue, Yasuhiro Yamashita + Show 1 more

https://doi.org/10.1039/d0gc04202a

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Journal: Green Chem.	Publication Date: Jan 1, 2021
Citations: 13

Abstract

A highly practical continuous-flow system for aldol reactions of ketones and trifluoroacetophenones has been developed.

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