High-Sensitivity Polarization Sensitive Optical Coherence Tomography Based on Numerical Correction for Perfect Circularly Polarized Light

Abstract

Polarization sensitive optical coherence tomography (PSOCT) makes use of the birefringence information of the sample to compensate for the lack of internal tissue-specific contrast in conventional optical coherence tomography (OCT). Circularly polarized light is always used as an incident beam in PSOCT, but it is difficult to have perfect in practice. The manual calibration method of circularly polarized light suffers from the problems of complicated calibration operation and lack of stability. This study proposes a simple method to enhance the imaging of PSOCT without altering the system. A numerical calibration of circularly polarized light can be implemented using the original system setup, ensuring that the system’s complexity remains unchanged. Enhancements in imaging quality can be achieved through an algorithmic analysis of the captured interference fringe data. This calibration is applied in the field map of interference data before being quadrature-assembled. Notably, the proposed approach achieves high sensitivity in PSOCT. The birefringence image shows a more obvious layered structure. Improvements in the signal-to-noise ratio (SNR) were demonstrated for chicken breast, pork, and beef imaging at about 20 dB.