Abstract
15 mg/m 2 was given, electroporation was performed by administration of pulsed high-intensity electric fields, in 20 minutes. Patient was discharged on POD 1. No early side effect was observed. Pathology showed a partial tumor regression (TRG3) confined to the mucosal layer. Main results: Patient underwent a careful follow up. One month after the procedure, he suffered from major fecal incontinence and proctoscopy showed a large rectal ulcer in the field of ECT. PET scan showed an increase of SUV. Patient refused abdominoperineal excision at all. Three months later, digital examination and proctoscopy showed a complete rectal mucosal healing, with a minimal residual scar and PET scan showed a minimal SUV. At the last follow up, 10 months after ECT, these results were confirmed. Fecal incontinence resolved completely. Conclusion: ECT has been proven effective in the treatment of cutaneous and subcutaneous tumors: its role in the palliative treatment of small low rectal tumors after neoadjuvant therapy is promising.
Published Version
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