Abstract
Background Quantitative first-pass CMR can assess the severity of microvascular coronary dysfunction(MCD) in subjects with signs and symptoms of ischemia but without obstructive coronary artery disease(CAD). In patients with MCD, abnormalities of myocardial perfusion reserve (MPR) occur globally but may also vary in their transmural extent. Thus, high spatial resolution quantitative CMR perfusion imaging is needed to differentiate between the subendocardial and subepicardial layers. Given the efficiency and SNR of spiral trajectories, we have developed the accelerated high-resolution absolute
Highlights
Quantitative first-pass CMR can assess the severity of microvascular coronary dysfunction(MCD) in subjects with signs and symptoms of ischemia but without obstructive coronary artery disease(CAD)
We developed an accelerated high-resolution perfusion pulse sequence based on our previous dual contrast quantitative spiral sequence
Resting perfusion were collected in 5 volunteers and adenosine stress CMR was performed in one suspected MCD patient
Summary
High-resolution quantitative spiral perfusion for microvascular coronary dysfunction detection. Yang Yang1*, Sujith Kuruvilla, Craig H Meyer, Frederick H Epstein, Angela M Taylor, Christopher M Kramer, Michael Salerno. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014
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