High-resolution multicontrast tomography with an X-ray microarray anode–structured target source

Abstract

Significance Talbot–Lau interferometry (TLI) holds remarkable potential for multicontrast X-ray imaging but suffers from technical challenges associated with microfabrication and limited efficiency. We tackle the frontier challenges in this field by developing a microarray anode–structured target source with a built-in structured illumination scheme. Our development facilitates high-resolution and high-sensitivity TLI imaging without the absorption source grating. We demonstrate the tri-contrast tomography capability with a Drum fish tooth specimen and separate the biological features with different combinations of physical properties. Our approach not only addresses the long-standing challenges in the field of X-ray TLI phase-contrast imaging but also features a compact setup that can potentially be made broadly available to academia research and industrial applications.