Abstract
We report the development of a Spectral Domain Line Field Optical Coherence Tomography (LF-OCT) system, using a broad bandwidth and spatial coherent Super-Continuum (SC) source. With conventional quasi-Continuous Wave (CW) setup we achieve axial resolutions up to 2.1 μm in air and 3D volume imaging speeds up to 213 kA-Scan/s. Furthermore, we report the use of a single SC pulse, of 2 ns duration, to temporally gate an OCT B-Scan image of 70 A-Scans. This is the equivalent of 35 GA-Scans/s. We apply the CW setup for high resolution imaging of the fine structures of a human cornea sample ex-vivo. The single pulse setup is applied to imaging of a coated pharmaceutical tablet. The fixed pattern noise due to spectral noise is removed by subtracting the median magnitude A-Scan. We also demonstrate that the Fourier phase can be used to remove aberration caused artefacts.
Highlights
Scanning Point (SP) spectrometer based Spectral Domain (SD) [1] and Swept Source (SS) [2] arrangements have become the standard Optical Coherence Tomography (OCT) [3, 4] setups in ophthalmic imaging [5, 6]
The theoretical and measured raw Point Spread Functions (PSFs) closely match, the Line Field Optical Coherence Tomography (LF-OCT) systems Linnik based design is free from significant broadening due to dispersion
A LF-OCT setup is demonstrated to be suitable for high quality ultra-high resolution imaging of the cornea and is able to take a B-Scan image in the temporal gate of a single laser pulse
Summary
Scanning Point (SP) spectrometer based Spectral Domain (SD) [1] and Swept Source (SS) [2] arrangements have become the standard Optical Coherence Tomography (OCT) [3, 4] setups in ophthalmic imaging [5, 6]. The first reason for this is that Fourier Domain (FD) (including SD and SS) OCT has higher intrinsic Signal to Noise Ratio (SNR) than earlier Time Domain (TD) systems [7, 8]. The second reason is that SP configuration gives confocal gating, which removes out of focus light and improves image quality. Motion artefacts are a profound problem for in-vivo imaging with SP OCT [9]. Heartbeat and respiration will cause distortion of the axial positions between A-scans. This problem has been alleviated by increasing scanning speed or introducing alignment solutions, but cannot be entirely resolved
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