Abstract
High-resolution at 3T for in vivo derivative NMR spectroscopy in medical diagnostics of ovarian tumor: exact quantification by shape estimations
Highlights
In nuclear magnetic resonance (NMR) spectroscopy, or magnetic resonance spectroscopy (MRS) as it is called in medical diagnostics, the main problems are low sensitivity, compared to all other spectroscopies
The time signals or free induction decay (FID) to be processed in this work have been kindly provided to us by our colleagues from the Department of Obstetrics/Gynecology and Laboratory of Pediatrics/Neurology, University Medical Centre Nijmegen, the Netherlands
Proton MRS was applied with single-voxel point-resolved spectroscopy sequence (PRESS)
Summary
In nuclear magnetic resonance (NMR) spectroscopy, or magnetic resonance spectroscopy (MRS) as it is called in medical diagnostics, the main problems are low sensitivity, compared to all other spectroscopies. Within the SNS concept, applying the FPT to in vivo MRS time signals encoded from the ovary, the role of spectral poles and zeros was examined, as the key to stability of the system to external perturbations [42]. [41, 42], it was demonstrated that spectra averaging and Padé-based extrapolation of time signals were crucial for the reconstructed poles and zeros, as well as for the associated magnitudes and phases This procedure was necessary to check the stability of the retrieved fundamental parameters and to accurately reconstruct all the physical component resonances. The Fourier nonderivative and derivative envelopes will be referred to as |FFT| and |DmFFT|, respectively
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