Abstract
An analytical method has been developed, using cation-exchange high-performance liquid chromatography, for the analysis of N-methylated metabolites of nicotine. This method has been used to detect and quantitate seven potential in vivo urinary metabolites of [2′- 14C]nicotine, including four methylated nicotine derivatives, in the guinea pig.
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Schedule a callMore From: Journal of Chromatography B: Biomedical Sciences and Applications
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