High current short pulse driver using a high power diode laser for optoacoustic biomedical imaging techniques.

Abstract

Optoacoustic biomedical imaging combines the high spatial resolution of the ultrasound imaging with the specificity of the optical absorption spectroscopy techniques. It is being used in various scenarios such as anatomical, functional and molecular imaging. Typically light sources for this imaging technique is based on solid state lasers since they can produce high energy short optical pulses. However, they are bulky, expensive and the imaging speed is limited because their low pulse repetition rate. High power diode lasers (HPDLs) are a promising alternative for imaging small volume absorbers as they are compact, affordable and allow high repetition rates. However, HPDLs provide relative low peak optical power compared to solid state lasers. Therefore, imaging systems based on diode lasers require much longer pulse duration resulting in lower in-depth resolution and optoacoustic conversion efficiency. HPDLs need dedicated fast electronics to generate short optical pulses. In this work, we have designed, built and test a pulsed diode laser driver based on RF power MOSFETs, specifically considering the optimization of the current pulse in order to maximize the optical peak power, achieving current pulses of more than 900 A with a duration of 50 ns. We have studied the operation of a low cost HPDL out of the manufacturers datasheet ratings without noticeable degradation at high current (> 250 A) and short pulse duration (< 60 ns). We have obtained an optical peak power of 750 W and a energy per pulse of 31.2 µJ at 40 ns optical pulse duration. The optoacoustic images obtained in this operation regime shown a clear enhancement respect to the ones obtained in standard operation of the HPDL.