Abstract

An iron(III) complex with tfda (2-aminomethyltetrahydrofuran-N,N-diacetic acid) exhibits high activity for hydroxylation at the 8 and 2′ positions of deoxyguanosine in the presence of hydrogen peroxide; this demonstrates that a facile transformation from deoxyribonucleotide to ribonucleotide in vivo may be possible.

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