Hierarchical Process Neural Network Model within Variable-Sampling Time

Abstract

The biochemical processes are usually described as seriously time varying and nonlinear dynamic systems. It is very costly and difficult to build their first-principle models due to the absence of inherent mechanism and efficient on-line sensors. In this paper, a hierarchical process neural network (HPNN) model within variable-sampling time has been proposed. Simulation is based on penicillin fed-batch fermentation process, shows that the model established is more accurately and efficient, and suffice for the requirements of control and optimization for biochemical processes.