Abstract
Hereditary and environmental epidemiology of sarcomas
Highlights
Despite being rare, sarcomas have acted as sentinel events that are epidemiologically noteworthy
Sarcomas such as gastrointestinal stromal tumor and dermatofibrosarcoma protuberans demonstrate the power of linking genetic mutations to effective targeted therapy
The most effective mechanism for improved survival lies in prevention and early detection. This has already been demonstrated by the application of screening procedures in populations affected by lung, bowel and breast cancers [9]
Summary
Despite (or perhaps because of ) being rare, sarcomas have acted as sentinel events that are epidemiologically noteworthy. Sarcomas such as gastrointestinal stromal tumor and dermatofibrosarcoma protuberans demonstrate the power of linking genetic mutations to effective targeted therapy.
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