Abstract
Traditional Medicines derived from medicinal plants are used by about 60% of the world population. This review focuses on Herbal drugs used in the treatment of Anxiety disorder. Anxiety disorders, including generalized anxiety disorder (GAD), panic disorder, post-traumatic stress disorder (PTSD), and obsessive compulsive disorder (OCD), are the most prevalent behavioral disorders in the United States, affecting 17.2% of the population. The use of herbal supplements to treat anxiety has been increasing and the mechanisms of action of several are being elucidated. A list of medicinal plants with proven antianxiety effects used in treatment of Anxiety is compiled. These include, Citrus paradise, Cirsium rivulare , Drymaria cordata, Colocasia esculenta, Souroubea sympetala, Rollinia mucosa, Aethusa cynapium, Uncaria rhynchophylla, Cinnamomum cassia, Gastrodia elata, Apocynum venetum, Turnera aphrodisiaca, Scutellaria lateriflora, Valeriana officinalis , Galphimia glauca etc.
Highlights
In the last few years there has been an exponential growth in the field of herbal medicine and these drugs are gaining popularity both in developing and developed countries because of their natural origin and less side effects
The current review focuses on herbal drug used in the treatment of anxiety disorders, among the most common mental disorders besides depressive disorders with approximately one-eighth of the world population affected at some point in their life [2]
Results show that methanol extract at the dose of 100mg/kg of the leaves of Citrus paradisi var. star ruby markedly increased the average time spent in the open arms of the elevated plus maze (EPM) [3]
Summary
In the last few years there has been an exponential growth in the field of herbal medicine and these drugs are gaining popularity both in developing and developed countries because of their natural origin and less side effects. The current review focuses on herbal drug used in the treatment of anxiety disorders, among the most common mental disorders besides depressive disorders with approximately one-eighth of the world population affected at some point in their life [2]. Citrus paradisi var.star ruby (Grapefruit): Citrus paradisi has been used traditionally to reduce stress and anxiety. The antianxiety activity of various extracts viz petroleum ether, chloroform, methanol and water, of the leaves of Citrus paradisi var. Star ruby using elevated plus maze (EPM) model in Swiss albino mice were evaluated. Results show that methanol extract at the dose of 100mg/kg of the leaves of Citrus paradisi var. Star ruby markedly increased the average time spent in the open arms of the EPM [3] Results show that methanol extract at the dose of 100mg/kg of the leaves of Citrus paradisi var. star ruby markedly increased the average time spent in the open arms of the EPM [3]
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