Abstract

This study was to investigate the hepatoprotective effects of sun-dried organic apricot (SDOA) supplementation to chow against acetaminophen(APAP)-induced acute hepatotoxicity in rats. In this study, 24 female rats were randomized into four groups (n=6/groups). Blood and liver tissue samples were subjected to biochemical and histological examinations. SDOA consumption have strongly hepatoprotective effects againist APAP- induced acute hepatotoxicity in rats. The SDOA supplementation over a 45-day feeding period showed a beneficial effect against APAP-induced acute hepatotoxicity in rats, as reflects by histologycal and biochemical findings. Therefore, for humans in case of overdose APAP administration or chronic APAP treatments apricot consumption may be recommended.

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