Abstract
One of the most important problems in treating hepatitis is the choice and rational use of hepatoprotective agents. The goal of the work was to compare the hepatoprotective activity of licorice and essential phospholipids from different manufacturers. The completed investigation found that three of four licorice preparations (glycyrrhizic acid, decoction of licorice root, and liquiriton) showed similar effectiveness whereas licorice syrup did not exhibit hepatoprotective activity. This indicated that triterpene and flavonoid glycosides contributed approximately equally to the hepatoprotective activity of licorice root. Preparations of essential phospholipid analogs had different efficiencies. Essentiale had the greatest hepatoprotective activity. Then, eslidin and essliver forte followed in descending order. The combined preparation phosphogliv showed the greatest effectiveness in therapy of experimental toxic hepatitis.
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