Hepatic and Lung Histiocytosis

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A 52-year-old male was admitted for abdominal pain. He had a personal history of tobacco. The physical examination and laboratory tests were normal. A thoraco-abdominal computed tomography scan (CT) reveals a combination of a thin walled pulmonary cystic lesion, and an hepatic hypodense subcapsular lesion (Figure 1). No other abnormalities were showed. The liver magnetic resonance imaging (MRI) showed a normal sized liver with regular contours and multiple nodular lesions (Figure 2). We completed by liver biopsy, that shows infiltration of large cells with irregular nuclei that positively stained to CD1a and S100 (Figure 3).