Abstract
Heparan Sulfate Proteoglycans: A Multifaceted Target for Novel Approaches in Antiviral Drug Discovery
Highlights
Viruses are the etiological cause of important human diseases worldwide
Viral infections tend to occur simultaneously, as it happens for human immunodeficiency virus (HIV) that, by inducing a severe immunodeficiency, causes an increase in human papilloma virus (HPV), herpes simplex virus (HSV) and respiratory syncytial virus (RSV) infections [1,2,3]
Based on their capacity to act as attachment receptors for different viruses, heparan sulfate proteoglycans (HSPGs) have been considered an attractive target for the development of multitarget antiviral drugs to prevent infections by those viruses that cannot be eliminated through classical antiviral treatment or protective vaccines
Summary
Heparan Sulfate Proteoglycans: A Multifaceted Target for Novel Approaches in Antiviral Drug Discovery.
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